•  Severe tubal factors (irreparable non functional fallopian tube)
•  Severe male factors
•  Severe egg factors (donor egg required since ovulation induction is impossible)
•  Endometriosis grade III and IV
•  Immunologic infertility
•  Unexplained infertility
•  Failed IUI treatment
•  Those who want immediate pregnancy
•  Ovulation failure with all possible conventional methods
•  Those are coming from abroad who can spare very little time
•  Unexplained Infertility
•  Women with vaginisms never had successful intercourse